[HTML][HTML] An ubiquitin-dependent balance between mitofusin turnover and fatty acids desaturation regulates mitochondrial fusion

L Cavellini, J Meurisse, J Findinier… - Nature …, 2017 - nature.com
… and maintenance of efficient mitochondrial fusion. Our results … regulates mitochondrial
fusion by coordinating an intricate balance between Fzo1 turnover and the status of fatty acids

Ubiquitin–proteasome-dependent degradation of a mitofusin, a critical regulator of mitochondrial fusion

MMJ Cohen, GP Leboucher… - … biology of the cell, 2008 - Am Soc Cell Biol
… by the equilibrium between ongoing fusion and fission of … by which Mdm30p regulates
mitochondrial morphology and … role for proteasomes in regulating the constitutive turnover of Fzo1 …

[HTML][HTML] The regulation of mitochondrial homeostasis by the ubiquitin proteasome system

C Alsayyah, O Ozturk, L Cavellini… - … et Biophysica Acta (BBA …, 2020 - Elsevier
… that the UPS employs to regulate mitochondrial function and … mitochondrial fusion upon high
desaturation of fatty acids but … or whether they control turnover of the mitofusin through other …

[HTML][HTML] Mitofusin-mediated contacts between mitochondria and peroxisomes regulate mitochondrial fusion

C Alsayyah, MK Singh, MA Morcillo-Parra… - PLoS …, 2024 - journals.plos.org
… , FA desaturation is triggered by the Δ9-fatty acid desaturase … that mitochondrial fusion is
governed by a balance betweenturnover is governed by the status of FA desaturation (Fig 3). …

Regulation of mitochondrial fusion by the Ubiquitin Proteasome System and physical contacts between mitochondria and peroxisomes in yeast Saccharomyces …

C Alsayyah - 2021 - theses.hal.science
… mitophagy is distinct from ubiquitin-dependent mitophagy, its … their biosynthesis and turnover
are tightly regulated. Membrane … and Mga2 is the fatty acid desaturase gene OLE1. Both …

Two Cdc48 cofactors Ubp3 and Ubx2 regulate mitochondrial morphology and protein turnover

A Chowdhury, T Ogura, M Esaki - The journal of biochemistry, 2018 - academic.oup.com
… is a homologue of mitofusins in mammals, on the mitochondrial outer … ubiquitin-dependent
cascades for Fzo1, Ubp2 and Ubp12 are intricately intertwined to regulate mitochondrial fusion

Cdc48 regulates a deubiquitylase cascade critical for mitochondrial fusion

T Simões, R Schuster, F den Brave… - elife, 2018 - elifesciences.org
… in ubiquitin-dependent regulation of mitochondrial dynamics. … signal Fzo1 turnover thus
preventing mitochondrial fusion. … p97 and ubiquitin regulate mitochondrial fusion in both yeast …

Mdm30 is an F-box protein required for maintenance of fusion-competent mitochondria in yeast

S Fritz, N Weinbach, B Westermann - Molecular biology of the cell, 2003 - Am Soc Cell Biol
… that Mdm30 controls mitochondrial shape by regulating the … To test the Mdm30-dependent
turnover of Fzo1 more directly we … ubiquitin-dependent processes that influence mitochondrial

A AAA ATPase Cdc48 with a cofactor Ubx2 facilitates ubiquitylation of a mitochondrial fusion-promoting factor Fzo1 for proteasomal degradation

S Nahar, A Chowdhury, T Ogura… - The journal of …, 2020 - academic.oup.com
turnover rate of Fzo1, but showed normal mitochondrial morphology. Thus, Ubp3 and Ubx2
seem independently to regulate mitochondrial … degraded in a ubiquitin-dependent manner (…

[HTML][HTML] Mitochondrial shaping cuts

M Escobar-Henriques, T Langer - … et Biophysica Acta (BBA)-Molecular Cell …, 2006 - Elsevier
… sensor regulating mitochondrial fusion through the balanced … E3 enzymes and ensure
ubiquitin-dependent degradation by 26S … biosynthesis of unsaturated fatty acids and multivesicular …